.cc-workspace{--cc-ink:#253540;--cc-muted:#627286;--cc-border:#dde3ed;--cc-purple:#5949b5;max-width:1160px;margin:0 auto;padding:42px 28px 64px;color:var(--cc-ink)}
.cc-workspace *{box-sizing:border-box}.cc-workspace :is(h1,h2,h3,p){margin:0}.cc-workspace p{line-height:1.6}.cc-workspace :is(button,input,select){font:inherit}.cc-workspace button{cursor:pointer}.cc-workspace button:disabled{cursor:default;opacity:.55}.cc-workspace [hidden]{display:none!important}.cc-workspace :is(button,input,select,summary,a):focus-visible{outline:3px solid #9384d6;outline-offset:3px}.cc-workspace a{color:#56479d;text-underline-offset:3px}.cc-workspace .section-heading{display:flex;align-items:center;gap:10px}.cc-workspace .section-help{flex:none}.cc-workspace h1{font-size:clamp(28px,3.5vw,38px);line-height:1.2;letter-spacing:-.9px}.cc-workspace h2{font-size:19px;line-height:1.35;letter-spacing:-.25px}.cc-workspace h3{font-size:16px;line-height:1.4}.cc-header{margin-bottom:28px}.cc-header>p{font-size:16px;color:var(--cc-muted);margin-top:11px}.cc-header>p.cc-gene-context,.cc-header>p.cc-scope{font-size:13px}.cc-explore-link{display:inline-block;font-size:13px;margin-top:16px}.cc-eyebrow{display:block;font-size:11px;letter-spacing:.065em;text-transform:uppercase;color:#6d608f;font-weight:650;margin-bottom:10px}.cc-panel{border:1px solid var(--cc-border);border-radius:15px;background:#fff;padding:24px;margin-bottom:18px}.cc-variant-fields{display:grid;grid-template-columns:repeat(2,minmax(0,1fr));gap:20px 24px;align-items:start;margin-top:18px}.cc-workspace label{margin:0;font-size:12px;font-weight:600;color:#586577;min-width:0}.cc-variant-fields label{display:grid;gap:8px}.cc-variant-fields label>small{font-size:11px;font-weight:400;line-height:1.5;color:var(--cc-muted)}.cc-workspace input:not([type=checkbox]),.cc-workspace select{border:1px solid #bcc7d8;background:#fff;border-radius:8px;width:100%;min-width:0;padding:11px;color:#253540;font-size:15px;font-weight:400;line-height:1.5}.cc-note{font-size:12px!important;color:var(--cc-muted);margin-top:11px!important}.cc-examples{display:grid;gap:10px;margin-top:22px}.cc-examples>span{font-size:12px;font-weight:600;color:var(--cc-muted)}.cc-example-list{display:grid;grid-template-columns:repeat(2,minmax(0,1fr));gap:10px;max-width:740px}.cc-example{display:grid;align-content:start;gap:7px;margin:0;border:1px solid #ddd8ed;background:#f8f6fd;color:#5b4f8e;border-radius:9px;padding:14px 16px;text-align:left;font-size:12px!important}.cc-example:only-child{grid-column:1/-1;max-width:580px}.cc-example>strong{font-size:14px}.cc-example>span{font-size:12px;font-weight:400;line-height:1.5;color:var(--cc-muted)}.cc-example>small{font-size:11px;font-weight:600;margin-top:3px}.cc-example:hover{border-color:#a696d0}.cc-contexts{display:grid;grid-template-columns:repeat(3,minmax(0,1fr));gap:12px;border:0;padding:0;margin:19px 0 0}.cc-context{display:flex;gap:10px;align-items:flex-start;border:1px solid #dde2ed;padding:15px;border-radius:10px;background:#fcfcfe;cursor:pointer}.cc-context:has(input:checked){border-color:#a696d0;background:#f7f4fd}.cc-context input{margin:3px 0 0;accent-color:var(--cc-purple);width:17px;height:17px;flex:none}.cc-context span{display:grid;gap:7px}.cc-context strong{font-size:13px;font-weight:600;color:#3d4561}.cc-context small{font-size:11px;font-weight:400;line-height:1.5;color:var(--cc-muted)}.cc-actions{display:flex;align-items:center;flex-wrap:wrap;gap:12px;margin-top:21px}.cc-primary,.cc-secondary{border-radius:9px;min-height:44px;padding:11px 17px;font-size:14px!important;font-weight:600!important}.cc-primary{color:white;background:var(--cc-purple);border:1px solid var(--cc-purple)}.cc-primary:hover:not(:disabled){background:#493a99}.cc-secondary{background:white;border:1px solid #c9cddd;color:#4e456c}.cc-actions>p{font-size:12px;color:var(--cc-muted);flex:1;min-width:160px}.cc-error{font-size:13px;color:#884b3c;background:#fff4f0;border:1px solid #eed4ca;border-radius:9px;padding:12px 14px;margin-top:15px!important}.cc-error:empty{display:none}.cc-loading{color:var(--cc-muted);font-size:14px;padding-bottom:18px}.cc-result{border:1px solid #dcd4eb;border-radius:15px;background:#fff;padding:26px;margin-top:29px}.cc-result-top{display:flex;align-items:flex-start;justify-content:space-between;gap:20px}.cc-result-top h2{font-size:22px;line-height:1.4}.cc-link{padding:5px 0;border:0;background:transparent;color:#584995;font-size:12px!important;text-decoration:underline;text-underline-offset:3px;white-space:nowrap}.cc-summary{font-size:15px;color:#586778;max-width:850px;margin-top:13px!important}.cc-dna{border:1px solid #e5e0ef;background:#f8f7fc;border-radius:9px;padding:14px 17px;margin-top:22px;max-width:100%;overflow:auto}.cc-dna>div{display:flex;align-items:center;gap:15px;margin:4px 0 9px}.cc-dna span{display:block;font-size:11px;color:#6d6481;min-width:60px}.cc-dna code{font:14px/1.8 ui-monospace,SFMono-Regular,Consolas,monospace;letter-spacing:1.5px;white-space:nowrap;color:#84919c}.cc-dna mark{padding:3px 2px;color:#314152;background:#dfe4ed;border-radius:3px}.cc-dna mark.cc-alt{color:#583b96;background:#e3d8f7}.cc-dna>p{font-size:10px;color:#706d82}.cc-dna-short{display:flex;gap:12px;align-items:center}.cc-dna-short span{min-width:0}.cc-dna-short code{color:#574195}.cc-cell-grid{display:grid;grid-template-columns:repeat(3,minmax(0,1fr));gap:14px;margin-top:22px}.cc-cell{padding:19px;border:1px solid var(--cc-border);border-radius:11px;min-width:0}.cc-readout{font-size:11px;color:var(--cc-muted);margin-top:8px!important}.cc-value{display:block;font-size:32px;letter-spacing:-1px;color:#56419b;margin-top:22px;line-height:1.15}.cc-direction{font-size:12px;color:#657084;margin-top:7px!important}.cc-cell-unavailable .cc-value{font-size:23px;color:#798394;letter-spacing:-.4px}.cc-bar{position:relative;height:14px;background:#f0eef5;border-radius:4px;margin-top:20px;overflow:hidden}.cc-bar i{position:absolute;display:block;height:100%;background:#8270c5;max-width:50%}.cc-bar i.cc-bar-negative{background:#628c99}.cc-bar-zero{position:absolute;top:0;bottom:0;left:50%;width:1px;background:#b4aac8;z-index:1}.cc-axis{display:flex;justify-content:space-between;font-size:10px;color:#8690a0;margin-top:6px}.cc-direction.cc-direction-mixed{color:#84632d;background:#fff8eb;border-radius:6px;padding:8px}.cc-scale-note{font-size:12px;color:#697586;margin-top:15px!important}.cc-details{border-top:1px solid #e5e4ed;margin-top:20px;padding-top:12px;color:#617083;font-size:12px;line-height:1.6}.cc-details>summary{color:#574c7c;font-weight:600;font-size:13px;cursor:pointer;padding:6px 0}.cc-details p,.cc-details .section-heading{margin-top:12px}.cc-details ul{padding-left:19px;margin:12px 0}.cc-details li{margin:6px 0}.cc-details h3{font-size:14px}.cc-consequences{display:grid;gap:10px;margin-top:16px}.cc-consequences>div{display:grid;grid-template-columns:100px 1fr;gap:5px 15px;align-items:baseline;padding:12px;border-radius:8px;background:#f8f9fc;overflow-wrap:anywhere}.cc-consequences strong{color:#405063}.cc-consequences code,.cc-consequences small{grid-column:2}.cc-consequences code{font-size:11px}.cc-sources{display:flex;gap:12px;flex-wrap:wrap;margin-top:14px}.cc-runtime{font-size:11px;color:#89929f;margin-top:17px!important}.cc-sr-only{position:absolute;width:1px;height:1px;padding:0;margin:-1px;overflow:hidden;clip:rect(0,0,0,0);white-space:nowrap;border:0}#cc-result-title{scroll-margin-top:24px}.cc-workspace .section-help-content{font-size:13px}
@media(max-width:820px){.cc-contexts,.cc-cell-grid{grid-template-columns:1fr}.cc-context{padding:14px}.cc-cell{padding:19px}.cc-cell .cc-value{margin-top:15px}.cc-cell .cc-bar{max-width:480px}.cc-cell .cc-axis{max-width:480px}}
@media(max-width:550px){.cc-workspace{padding:26px 16px 46px}.cc-panel,.cc-result{padding:18px}.cc-header>p{font-size:14px}.cc-variant-fields{grid-template-columns:1fr 1fr;gap:14px}.cc-variant-fields label:nth-of-type(1),.cc-variant-fields label:nth-of-type(2){grid-row:1}.cc-variant-fields label:nth-of-type(3),.cc-variant-fields label:nth-of-type(4){grid-row:2}.cc-result-top{flex-direction:column;gap:10px}.cc-result-top h2{font-size:20px}.cc-dna{padding:12px}.cc-dna>div{display:grid;gap:3px}.cc-dna code{font-size:11px;letter-spacing:.5px}.cc-actions>p{flex-basis:100%}.cc-actions>.cc-primary{flex:1}.cc-consequences>div{grid-template-columns:1fr;gap:3px}.cc-consequences code,.cc-consequences small{grid-column:1}.cc-summary{font-size:14px}.cc-example-list{grid-template-columns:1fr}.cc-example{padding:12px 14px}}
@media(prefers-reduced-motion:reduce){.cc-workspace *{scroll-behavior:auto;transition:none;animation:none}}
.cc-lookup{display:flex;gap:12px;align-items:flex-end;margin-top:20px;max-width:460px}.cc-lookup label{margin:0;display:grid;grid-template-columns:1fr auto;gap:7px;flex:1}.cc-lookup input{grid-column:1/-1}.cc-lookup .cc-secondary{min-height:47px;white-space:nowrap;font-size:12px!important}.cc-allele-choice{display:grid;gap:8px;margin-top:15px;max-width:350px}.cc-studied article{border-top:1px solid #e7e7ee;margin-top:16px;padding-top:16px}.cc-studied article h3{line-height:1.5}.cc-studied article:first-of-type{border-top:0;padding-top:0}
.cc-baseline{display:flex;align-items:center;gap:7px;font-size:11px;line-height:1.5;padding:8px 10px;margin-top:12px;border-radius:7px;background:#f3f5f8;color:#6b7482}.cc-baseline-overlap{background:#eff7f3;color:#386b57}.cc-baseline-absent{background:#faf6ed;color:#7d6846}.cc-baseline .section-help-trigger{width:30px;height:30px;min-height:30px;font-size:11px}.cc-baseline>span{flex:1}

.cc-disclosure{border-top:1px solid #e5e4ed;margin-top:20px;padding-top:12px}.cc-disclosure>.cc-details{border-top:0;margin-top:0;padding-top:0}.cc-disclosure>.section-help{margin-top:1px}

.cc-manual{border:0;border-top:1px solid var(--cc-border);margin:22px 0 0;padding:15px 0 0}.cc-manual>summary{font-size:13px;font-weight:600;color:#594a86;cursor:pointer;padding:5px 0}.cc-variant-summary{font-size:13px;line-height:1.6;overflow-wrap:anywhere;background:#f3f1fa;border:1px solid #e0d9ef;border-radius:8px;padding:12px 14px;margin-top:16px}.cc-note:empty{display:none}.cc-workspace [aria-invalid=true]{border-color:#b86147!important}
.cc-handoff{margin-top:18px}.cc-handoff-dna{display:flex;align-items:center;gap:20px;flex-wrap:wrap;border:1px solid #e0d9ef;border-radius:10px;background:#f8f6fd;padding:18px 20px}.cc-handoff-dna>div{display:grid;gap:7px;min-width:0}.cc-handoff-dna>div>span{font-size:12px;color:var(--cc-muted)}.cc-handoff-dna code{font:600 20px/1.4 ui-monospace,SFMono-Regular,Consolas,monospace;letter-spacing:2px;overflow-wrap:anywhere;color:var(--cc-purple)}.cc-handoff>.cc-link{display:inline-block;margin-top:10px;min-height:36px}.cc-workspace input[readonly]{background:#f8f9fc}
@media(max-width:550px){.cc-handoff-dna{display:grid;grid-template-columns:minmax(0,1fr) auto minmax(0,1fr);gap:10px;padding:14px 12px}.cc-handoff-dna code{font-size:14px;letter-spacing:.6px}}